diff --git a/.github/workflows/build_deps.yml b/.github/workflows/build_deps.yml
index f45394adf1..4a29a133a1 100644
--- a/.github/workflows/build_deps.yml
+++ b/.github/workflows/build_deps.yml
@@ -97,7 +97,7 @@ jobs:
             libwayland-dev libxkbcommon-dev wayland-protocols extra-cmake-modules pkgconf \
             libglu1-mesa-dev libcairo2-dev libgtk-3-dev libsoup2.4-dev libwebkit2gtk-${{ env.webkit-ver }}-dev \
             libgstreamer1.0-dev libgstreamer-plugins-good1.0-dev libgstreamer-plugins-base1.0-dev \
-            gstreamer1.0-plugins-bad libosmesa6-dev wget sudo autoconf curl libunwind-dev texinfo
+            gstreamer1.0-plugins-bad wget sudo autoconf curl libunwind-dev texinfo
 
       - name: Build on Ubuntu
         if: inputs.os == 'ubuntu-20.04' || inputs.os == 'ubuntu-24.04'
diff --git a/.github/workflows/build_orca.yml b/.github/workflows/build_orca.yml
index 1102895cc0..1ae30f7b3b 100644
--- a/.github/workflows/build_orca.yml
+++ b/.github/workflows/build_orca.yml
@@ -243,7 +243,7 @@ jobs:
           ${{ env.apt-cmd }} install -y autoconf build-essential cmake curl eglexternalplatform-dev \
           extra-cmake-modules file git libcairo2-dev libcurl4-openssl-dev libdbus-1-dev libglew-dev libglu1-mesa-dev \
           libglu1-mesa-dev libgstreamer1.0-dev libgstreamerd-3-dev libgstreamer-plugins-base1.0-dev libgstreamer-plugins-good1.0-dev \
-          libgtk-3-dev libgtk-3-dev libmspack-dev libosmesa6-dev libsecret-1-dev libsoup2.4-dev libssl-dev libudev-dev libwayland-dev \
+          libgtk-3-dev libgtk-3-dev libmspack-dev libsecret-1-dev libsoup2.4-dev libssl-dev libudev-dev libwayland-dev \
           libwebkit2gtk-${{ env.webkit-ver }}-dev libxkbcommon-dev locales locales-all m4 pkgconf sudo wayland-protocols wget ${{ env.libfuse2-pkg }}
 
       - name: Install dependencies from build_linux.sh
diff --git a/Dockerfile b/Dockerfile
index db9bf705e1..0cc12ac2aa 100644
--- a/Dockerfile
+++ b/Dockerfile
@@ -32,7 +32,6 @@ RUN apt-get update && apt-get install  -y \
     libgstreamer-plugins-good1.0-dev \
     libgtk-3-dev \
     libgtk-3-dev \
-    libosmesa6-dev \
     libsecret-1-dev \
     libsoup2.4-dev \
     libssl3 \
diff --git a/deps/GLEW/glew/README.md b/deps/GLEW/glew/README.md
index bfec3064de..475c69afc8 100644
--- a/deps/GLEW/glew/README.md
+++ b/deps/GLEW/glew/README.md
@@ -22,7 +22,6 @@ https://github.com/nigels-com/glew
 		* [Install build tools](#install-build-tools)
 		* [Build](#build-1)
 		* [Linux EGL](#linux-egl)
-		* [Linux OSMesa](#linux-osmesa)
 		* [Linux mingw-w64](#linux-mingw-w64)
 	* [Using cmake](#using-cmake)
 		* [Install build tools](#install-build-tools-1)
@@ -95,11 +94,6 @@ _Note: you may need to call `make` in the  **auto** folder first_
 	$ sudo apt install libegl1-mesa-dev
 	$ make SYSTEM=linux-egl
 
-##### Linux OSMesa
-
-	$ sudo apt install libosmesa-dev
-	$ make SYSTEM=linux-osmesa
-
 ##### Linux mingw-w64
 
 	$ sudo apt install mingw-w64
@@ -140,7 +134,6 @@ RedHat/CentOS/Fedora: `$ sudo yum install libXmu-devel libXi-devel libGL-devel c
 | --------------- | ----------- |
 | BUILD_UTILS     | Build the `glewinfo` and `visualinfo` executables. |
 | GLEW_REGAL      | Build in Regal mode. |
-| GLEW_OSMESA     | Build in off-screen Mesa mode. |
 | BUILD_FRAMEWORK | Build as MacOSX Framework.  Setting `CMAKE_INSTALL_PREFIX` to `/Library/Frameworks` is recommended. |
 
 ### Windows
diff --git a/doc/How-to-build.md b/doc/How-to-build.md
index c414bad3be..2377656e08 100644
--- a/doc/How-to-build.md
+++ b/doc/How-to-build.md
@@ -172,7 +172,6 @@ All required dependencies will be installed automatically by the provided shell
 - libgstreamerd-3-dev
 - libsecret-1-dev
 - libwebkit2gtk-4.0-dev
-- libosmesa6-dev
 - libssl-dev
 - libcurl4-openssl-dev
 - eglexternalplatform-dev
diff --git a/flatpak/io.github.softfever.OrcaSlicer.yml b/flatpak/io.github.softfever.OrcaSlicer.yml
index 2f588045d3..3dde299a64 100755
--- a/flatpak/io.github.softfever.OrcaSlicer.yml
+++ b/flatpak/io.github.softfever.OrcaSlicer.yml
@@ -36,29 +36,6 @@ modules:
         url: https://gstreamer.freedesktop.org/src/gst-plugins-good/gst-plugins-good-1.22.8.tar.xz
         sha256: e305b9f07f52743ca481da0a4e0c76c35efd60adaf1b0694eb3bb021e2137e39
 
-  # For libOSMesa
-  - name: mesa
-    buildsystem: meson
-    config-opts:
-      - -Dosmesa=classic
-      - -Ddri-drivers=[]
-      - -Dgallium-drivers=[]
-      - -Dvulkan-drivers=[]
-      - -Dplatforms=[]
-    build-options:
-      arch:
-        aarch64:
-          config-opts:
-            - -Dlibunwind=disabled
-    cleanup:
-      - /share/drirc.d
-      - /include
-      - "*.a"
-    sources:
-      - type: archive
-        url: https://archive.mesa3d.org/older-versions/20.x/mesa-20.2.6.tar.xz
-        sha256: f12ca3c6c622f11cd79ad66b4220f04514fa96f795062fe92a37339ab19885db
-
   - name: glu
     config-opts:
       - --disable-static
diff --git a/linux.d/debian b/linux.d/debian
index 121e53a3a7..cce41d74ce 100644
--- a/linux.d/debian
+++ b/linux.d/debian
@@ -15,7 +15,6 @@ REQUIRED_DEV_PACKAGES=(
     libgstreamerd-3-dev
     libgtk-3-dev
     libmspack-dev
-    libosmesa6-dev
     libsecret-1-dev
     libspnav-dev
     libssl-dev
diff --git a/linux.d/fedora b/linux.d/fedora
index bdfe05d567..ed91883dd9 100644
--- a/linux.d/fedora
+++ b/linux.d/fedora
@@ -22,7 +22,6 @@ REQUIRED_DEV_PACKAGES=(
     libtool
     m4
     mesa-libGLU-devel
-    mesa-libOSMesa-devel
     ninja-build
     openssl-devel
     perl-FindBin
diff --git a/src/slic3r/CMakeLists.txt b/src/slic3r/CMakeLists.txt
index b3a28a1c6b..903b66368b 100644
--- a/src/slic3r/CMakeLists.txt
+++ b/src/slic3r/CMakeLists.txt
@@ -640,9 +640,9 @@ elseif (CMAKE_SYSTEM_NAME STREQUAL "Linux")
     FIND_LIBRARY(WAYLAND_EGL_LIBRARIES    NAMES wayland-egl)
     FIND_LIBRARY(WAYLAND_CLIENT_LIBRARIES NAMES wayland-client)
     find_package(CURL REQUIRED)
-    target_link_libraries(libslic3r_gui ${DBUS_LIBRARIES} OSMesa)
     target_link_libraries(libslic3r_gui
         OpenGL::EGL
+        ${DBUS_LIBRARIES}
         ${WAYLAND_SERVER_LIBRARIES}
         ${WAYLAND_EGL_LIBRARIES}
         ${WAYLAND_CLIENT_LIBRARIES}