diff --git a/cura/Settings/MachineManager.py b/cura/Settings/MachineManager.py
index 2264038472..651714c005 100755
--- a/cura/Settings/MachineManager.py
+++ b/cura/Settings/MachineManager.py
@@ -637,6 +637,8 @@ class MachineManager(QObject):
         buildplate_compatible = True  # It is compatible by default
         extruder_stacks = self._global_container_stack.extruders.values()
         for stack in extruder_stacks:
+            if not stack.isEnabled:
+                continue
             material_container = stack.material
             if material_container == self._empty_material_container:
                 continue
diff --git a/plugins/CuraEngineBackend/StartSliceJob.py b/plugins/CuraEngineBackend/StartSliceJob.py
index aee6a46e5b..ed7731f6ec 100644
--- a/plugins/CuraEngineBackend/StartSliceJob.py
+++ b/plugins/CuraEngineBackend/StartSliceJob.py
@@ -131,6 +131,8 @@ class StartSliceJob(Job):
 
         for position, extruder_stack in stack.extruders.items():
             material = extruder_stack.findContainer({"type": "material"})
+            if not extruder_stack.isEnabled:
+                continue
             if material:
                 if material.getMetaDataEntry("compatible") == False:
                     self.setResult(StartJobResult.MaterialIncompatible)