diff --git a/plugins/VersionUpgrade/VersionUpgrade45to46/VersionUpgrade45to46.py b/plugins/VersionUpgrade/VersionUpgrade45to46/VersionUpgrade45to46.py
new file mode 100644
index 0000000000..378e1fd5d7
--- /dev/null
+++ b/plugins/VersionUpgrade/VersionUpgrade45to46/VersionUpgrade45to46.py
@@ -0,0 +1,74 @@
+# Copyright (c) 2020 Ultimaker B.V.
+# Cura is released under the terms of the LGPLv3 or higher.
+
+import configparser
+from typing import Tuple, List
+import io
+from UM.VersionUpgrade import VersionUpgrade
+
+_removed_settings = {
+    "machine_filament_park_distance"
+}
+
+class VersionUpgrade45to46(VersionUpgrade):
+    def getCfgVersion(self, serialised: str) -> int:
+        parser = configparser.ConfigParser(interpolation = None)
+        parser.read_string(serialised)
+        format_version = int(parser.get("general", "version"))  # Explicitly give an exception when this fails. That means that the file format is not recognised.
+        setting_version = int(parser.get("metadata", "setting_version", fallback = "0"))
+        return format_version * 1000000 + setting_version
+
+    ##  Upgrades Preferences to have the new version number.
+    #
+    #   This renames the renamed settings in the list of visible settings.
+    def upgradePreferences(self, serialized: str, filename: str) -> Tuple[List[str], List[str]]:
+        parser = configparser.ConfigParser(interpolation = None)
+        parser.read_string(serialized)
+
+        # Update version number.
+        parser["metadata"]["setting_version"] = "12"
+
+        # Remove deleted settings from the visible settings list.
+        visible_settings = set(parser["general"]["visible_settings"].split(";"))
+        for removed in _removed_settings:
+            if removed in visible_settings:
+                visible_settings.remove(removed)
+        parser["general"]["visible_settings"] = ";".join(visible_settings)
+
+        result = io.StringIO()
+        parser.write(result)
+        return [filename], [result.getvalue()]
+
+    ##  Upgrades instance containers to have the new version
+    #   number.
+    #
+    #   This renames the renamed settings in the containers.
+    def upgradeInstanceContainer(self, serialized: str, filename: str) -> Tuple[List[str], List[str]]:
+        parser = configparser.ConfigParser(interpolation = None, comment_prefixes = ())
+        parser.read_string(serialized)
+
+        # Update version number.
+        parser["metadata"]["setting_version"] = "12"
+
+        if "values" in parser:
+            for removed in _removed_settings:
+                if removed in parser["values"]:
+                    del parser["values"][removed]
+
+        result = io.StringIO()
+        parser.write(result)
+        return [filename], [result.getvalue()]
+
+    ##  Upgrades stacks to have the new version number.
+    def upgradeStack(self, serialized: str, filename: str) -> Tuple[List[str], List[str]]:
+        parser = configparser.ConfigParser(interpolation = None)
+        parser.read_string(serialized)
+
+        # Update version number.
+        if "metadata" not in parser:
+            parser["metadata"] = {}
+        parser["metadata"]["setting_version"] = "12"
+
+        result = io.StringIO()
+        parser.write(result)
+        return [filename], [result.getvalue()]
diff --git a/plugins/VersionUpgrade/VersionUpgrade45to46/__init__.py b/plugins/VersionUpgrade/VersionUpgrade45to46/__init__.py
new file mode 100644
index 0000000000..e44a02f704
--- /dev/null
+++ b/plugins/VersionUpgrade/VersionUpgrade45to46/__init__.py
@@ -0,0 +1,59 @@
+# Copyright (c) 2020 Ultimaker B.V.
+# Cura is released under the terms of the LGPLv3 or higher.
+
+from typing import Any, Dict, TYPE_CHECKING
+
+from . import VersionUpgrade45to46
+
+if TYPE_CHECKING:
+    from UM.Application import Application
+
+upgrade = VersionUpgrade45to46.VersionUpgrade45to46()
+
+def getMetaData() -> Dict[str, Any]:
+    return {
+        "version_upgrade": {
+            # From                           To                              Upgrade function
+            ("preferences", 6000011):        ("preferences", 6000012,        upgrade.upgradePreferences),
+            ("machine_stack", 4000011):      ("machine_stack", 4000012,      upgrade.upgradeStack),
+            ("extruder_train", 4000011):     ("extruder_train", 4000012,     upgrade.upgradeStack),
+            ("definition_changes", 4000011): ("definition_changes", 4000012, upgrade.upgradeInstanceContainer),
+            ("quality_changes", 4000011):    ("quality_changes", 4000012,    upgrade.upgradeInstanceContainer),
+            ("quality", 4000011):            ("quality", 4000012,            upgrade.upgradeInstanceContainer),
+            ("user", 4000011):               ("user", 4000012,               upgrade.upgradeInstanceContainer),
+        },
+        "sources": {
+            "preferences": {
+                "get_version": upgrade.getCfgVersion,
+                "location": {"."}
+            },
+            "machine_stack": {
+                "get_version": upgrade.getCfgVersion,
+                "location": {"./machine_instances"}
+            },
+            "extruder_train": {
+                "get_version": upgrade.getCfgVersion,
+                "location": {"./extruders"}
+            },
+            "definition_changes": {
+                "get_version": upgrade.getCfgVersion,
+                "location": {"./definition_changes"}
+            },
+            "quality_changes": {
+                "get_version": upgrade.getCfgVersion,
+                "location": {"./quality_changes"}
+            },
+            "quality": {
+                "get_version": upgrade.getCfgVersion,
+                "location": {"./quality"}
+            },
+            "user": {
+                "get_version": upgrade.getCfgVersion,
+                "location": {"./user"}
+            }
+        }
+    }
+
+
+def register(app: "Application") -> Dict[str, Any]:
+    return {"version_upgrade": upgrade}
diff --git a/plugins/VersionUpgrade/VersionUpgrade45to46/plugin.json b/plugins/VersionUpgrade/VersionUpgrade45to46/plugin.json
new file mode 100644
index 0000000000..ceabdb6d9d
--- /dev/null
+++ b/plugins/VersionUpgrade/VersionUpgrade45to46/plugin.json
@@ -0,0 +1,8 @@
+{
+    "name": "Version Upgrade 4.5 to 4.6",
+    "author": "Ultimaker B.V.",
+    "version": "1.0.0",
+    "description": "Upgrades configurations from Cura 4.5 to Cura 4.6.",
+    "api": "7.1",
+    "i18n-catalog": "cura"
+}