diff --git a/cura/Settings/MachineManager.py b/cura/Settings/MachineManager.py
index fd77c9fc85..66512e6c3c 100755
--- a/cura/Settings/MachineManager.py
+++ b/cura/Settings/MachineManager.py
@@ -324,8 +324,8 @@ class MachineManager(QObject):
                 Logger.log("i", "Machine '%s' quality changes set to '%s'",
                            global_stack.getName(), new_quality_changes_group.name)
         else:
-            if quality_type in quality_groups:
-                new_quality_group = quality_groups[quality_type]
+            new_quality_group = quality_groups.get(quality_type)
+            if new_quality_group is not None:
                 self._setQualityGroup(new_quality_group, empty_quality_changes = True)
                 same_quality_found = True
                 Logger.log("i", "Machine '%s' quality set to '%s'",
diff --git a/resources/qml/Preferences/ProfilesPage.qml b/resources/qml/Preferences/ProfilesPage.qml
index 1726087e97..7459ab6afc 100644
--- a/resources/qml/Preferences/ProfilesPage.qml
+++ b/resources/qml/Preferences/ProfilesPage.qml
@@ -71,7 +71,7 @@ Item
         {
             text: catalog.i18nc("@action:button", "Activate")
             iconName: "list-activate"
-            enabled: !isCurrentItemActivated
+            enabled: !isCurrentItemActivated && base.currentItem.quality_group != undefined
             onClicked: {
                 if (base.currentItem.is_read_only) {
                     Cura.MachineManager.setQualityGroup(base.currentItem.quality_group);
@@ -101,7 +101,7 @@ Item
         {
             text: catalog.i18nc("@label", "Duplicate")
             iconName: "list-add"
-            enabled: !base.canCreateProfile
+            enabled: !base.canCreateProfile && base.currentItem.quality_group != undefined
             visible: !base.canCreateProfile
 
             onClicked: {