diff --git a/plugins/SimulationView/SimulationPass.py b/plugins/SimulationView/SimulationPass.py
index 24bdedd368..b720fc5758 100644
--- a/plugins/SimulationView/SimulationPass.py
+++ b/plugins/SimulationView/SimulationPass.py
@@ -77,7 +77,7 @@ class SimulationPass(RenderPass):
             self._layer_shader.setUniformValue("u_max_thickness", 1)
             self._layer_shader.setUniformValue("u_min_thickness", 0)
             self._layer_shader.setUniformValue("u_layer_view_type", 1)
-            self._layer_shader.setUniformValue("u_extruder_opacity", [1, 1, 1, 1])
+            self._layer_shader.setUniformValue("u_extruder_opacity", [[1, 1, 1, 1], [1, 1, 1, 1], [1, 1, 1, 1], [1, 1, 1, 1]])
             self._layer_shader.setUniformValue("u_show_travel_moves", 0)
             self._layer_shader.setUniformValue("u_show_helpers", 1)
             self._layer_shader.setUniformValue("u_show_skin", 1)
diff --git a/plugins/SimulationView/SimulationView.py b/plugins/SimulationView/SimulationView.py
index 28d10c5f40..7a3fde494d 100644
--- a/plugins/SimulationView/SimulationView.py
+++ b/plugins/SimulationView/SimulationView.py
@@ -12,6 +12,7 @@ from UM.Event import Event, KeyEvent
 from UM.Job import Job
 from UM.Logger import Logger
 from UM.Math.Color import Color
+from UM.Math.Matrix import Matrix
 from UM.Mesh.MeshBuilder import MeshBuilder
 from UM.Message import Message
 from UM.Platform import Platform
@@ -139,7 +140,7 @@ class SimulationView(CuraView):
     def _resetSettings(self) -> None:
         self._layer_view_type = 0  # type: int # 0 is material color, 1 is color by linetype, 2 is speed, 3 is layer thickness
         self._extruder_count = 0
-        self._extruder_opacity = [1.0, 1.0, 1.0, 1.0]
+        self._extruder_opacity = [[1.0, 1.0, 1.0, 1.0], [1.0, 1.0, 1.0, 1.0], [1.0, 1.0, 1.0, 1.0], [1.0, 1.0, 1.0, 1.0]]
         self._show_travel_moves = False
         self._show_helpers = True
         self._show_skin = True
@@ -308,15 +309,15 @@ class SimulationView(CuraView):
 
     ##  Set the extruder opacity
     #
-    #   \param extruder_nr 0..3
+    #   \param extruder_nr 0..15
     #   \param opacity 0.0 .. 1.0
     def setExtruderOpacity(self, extruder_nr: int, opacity: float) -> None:
-        if 0 <= extruder_nr <= 3:
-            self._extruder_opacity[extruder_nr] = opacity
+        if 0 <= extruder_nr <= 15:
+            self._extruder_opacity[extruder_nr // 4][extruder_nr % 4] = opacity
             self.currentLayerNumChanged.emit()
 
-    def getExtruderOpacities(self)-> List[float]:
-        return self._extruder_opacity
+    def getExtruderOpacities(self) -> Matrix:
+        return Matrix(self._extruder_opacity)
 
     def setShowTravelMoves(self, show):
         self._show_travel_moves = show
diff --git a/plugins/SimulationView/layers.shader b/plugins/SimulationView/layers.shader
index 11b049c9fe..b68289aa6f 100644
--- a/plugins/SimulationView/layers.shader
+++ b/plugins/SimulationView/layers.shader
@@ -152,7 +152,7 @@ fragment41core =
 u_active_extruder = 0.0
 u_shade_factor = 0.60
 u_layer_view_type = 0
-u_extruder_opacity = [1.0, 1.0, 1.0, 1.0]
+u_extruder_opacity = [[1.0, 1.0, 1.0, 1.0],[1.0, 1.0, 1.0, 1.0],[1.0, 1.0, 1.0, 1.0],[1.0, 1.0, 1.0, 1.0]]
 
 u_show_travel_moves = 0
 u_show_helpers = 1
diff --git a/plugins/SimulationView/layers3d.shader b/plugins/SimulationView/layers3d.shader
index 518d03c974..56b50216a6 100644
--- a/plugins/SimulationView/layers3d.shader
+++ b/plugins/SimulationView/layers3d.shader
@@ -11,7 +11,7 @@ vertex41core =
     uniform lowp float u_max_thickness;
     uniform lowp float u_min_thickness;
     uniform lowp int u_layer_view_type;
-    uniform lowp vec4 u_extruder_opacity;  // currently only for max 4 extruders, others always visible
+    uniform lowp mat4 u_extruder_opacity;  // currently only for max 16 extruders, others always visible
 
     uniform highp mat4 u_normalMatrix;
 
@@ -31,7 +31,7 @@ vertex41core =
     out highp vec3 v_normal;
     out lowp vec2 v_line_dim;
     out highp int v_extruder;
-    out highp vec4 v_extruder_opacity;
+    out highp mat4 v_extruder_opacity;
     out float v_line_type;
 
     out lowp vec4 f_color;
@@ -121,7 +121,7 @@ geometry41core =
     in vec3 v_normal[];
     in vec2 v_line_dim[];
     in int v_extruder[];
-    in vec4 v_extruder_opacity[];
+    in mat4 v_extruder_opacity[];
     in float v_line_type[];
 
     out vec4 f_color;
@@ -152,7 +152,7 @@ geometry41core =
         float size_x;
         float size_y;
 
-        if ((v_extruder_opacity[0][v_extruder[0]] == 0.0) && (v_line_type[0] != 8) && (v_line_type[0] != 9)) {
+        if ((v_extruder_opacity[0][int(mod(v_extruder[0], 4))][v_extruder[0]/4] == 0.0) && (v_line_type[0] != 8) && (v_line_type[0] != 9)) {
             return;
         }
         // See LayerPolygon; 8 is MoveCombingType, 9 is RetractionType
@@ -304,7 +304,7 @@ fragment41core =
 [defaults]
 u_active_extruder = 0.0
 u_layer_view_type = 0
-u_extruder_opacity = [1.0, 1.0, 1.0, 1.0]
+u_extruder_opacity = [[1.0, 1.0, 1.0, 1.0], [1.0, 1.0, 1.0, 1.0], [1.0, 1.0, 1.0, 1.0], [1.0, 1.0, 1.0, 1.0]]
 
 u_specularColor = [0.4, 0.4, 0.4, 1.0]
 u_ambientColor = [0.3, 0.3, 0.3, 0.0]
diff --git a/plugins/SimulationView/layers3d_shadow.shader b/plugins/SimulationView/layers3d_shadow.shader
index b2ed7f8c12..88268938c9 100644
--- a/plugins/SimulationView/layers3d_shadow.shader
+++ b/plugins/SimulationView/layers3d_shadow.shader
@@ -6,7 +6,7 @@ vertex41core =
     uniform highp mat4 u_projectionMatrix;
 
     uniform lowp float u_active_extruder;
-    uniform lowp vec4 u_extruder_opacity;  // currently only for max 4 extruders, others always visible
+    uniform lowp mat4 u_extruder_opacity;  // currently only for max 16 extruders, others always visible
 
     uniform highp mat4 u_normalMatrix;
 
@@ -25,7 +25,7 @@ vertex41core =
     out highp vec3 v_normal;
     out lowp vec2 v_line_dim;
     out highp int v_extruder;
-    out highp vec4 v_extruder_opacity;
+    out highp mat4 v_extruder_opacity;
     out float v_line_type;
 
     out lowp vec4 f_color;
@@ -75,7 +75,7 @@ geometry41core =
     in vec3 v_normal[];
     in vec2 v_line_dim[];
     in int v_extruder[];
-    in vec4 v_extruder_opacity[];
+    in mat4 v_extruder_opacity[];
     in float v_line_type[];
 
     out vec4 f_color;
@@ -106,7 +106,7 @@ geometry41core =
         float size_x;
         float size_y;
 
-        if ((v_extruder_opacity[0][v_extruder[0]] == 0.0) && (v_line_type[0] != 8) && (v_line_type[0] != 9)) {
+        if ((v_extruder_opacity[0][int(mod(v_extruder[0], 4))][v_extruder[0] / 4] == 0.0) && (v_line_type[0] != 8) && (v_line_type[0] != 9)) {
             return;
         }
         // See LayerPolygon; 8 is MoveCombingType, 9 is RetractionType
@@ -256,7 +256,7 @@ fragment41core =
 
 [defaults]
 u_active_extruder = 0.0
-u_extruder_opacity = [1.0, 1.0, 1.0, 1.0]
+u_extruder_opacity = [[1.0, 1.0, 1.0, 1.0], [1.0, 1.0, 1.0, 1.0], [1.0, 1.0, 1.0, 1.0], [1.0, 1.0, 1.0, 1.0]]
 
 u_specularColor = [0.4, 0.4, 0.4, 1.0]
 u_ambientColor = [0.3, 0.3, 0.3, 0.0]
diff --git a/plugins/SimulationView/layers_shadow.shader b/plugins/SimulationView/layers_shadow.shader
index 8f500536a5..4bc2de3d0b 100644
--- a/plugins/SimulationView/layers_shadow.shader
+++ b/plugins/SimulationView/layers_shadow.shader
@@ -157,7 +157,7 @@ fragment41core =
 u_active_extruder = 0.0
 u_shade_factor = 0.60
 u_layer_view_type = 0
-u_extruder_opacity = [1.0, 1.0, 1.0, 1.0]
+u_extruder_opacity = [[1.0, 1.0, 1.0, 1.0], [1.0, 1.0, 1.0, 1.0], [1.0, 1.0, 1.0, 1.0], [1.0, 1.0, 1.0, 1.0]]
 
 u_show_travel_moves = 0
 u_show_helpers = 1