diff --git a/cura/Settings/ExtruderManager.py b/cura/Settings/ExtruderManager.py
index 8fa0172305..6e462031dc 100755
--- a/cura/Settings/ExtruderManager.py
+++ b/cura/Settings/ExtruderManager.py
@@ -344,7 +344,9 @@ class ExtruderManager(QObject):
             self._fixSingleExtrusionMachineExtruderDefinition(global_stack)
             if extruders_changed:
                 self.extrudersChanged.emit(global_stack_id)
-                self.setActiveExtruderIndex(0)
+
+                # Set it directly instead of using setActiveExtruder, since we want to force the signal to emitted.
+                self._active_extruder_index =  0
                 self.activeExtruderChanged.emit()
 
     # After 3.4, all single-extrusion machines have their own extruder definition files instead of reusing
diff --git a/cura/Settings/MachineManager.py b/cura/Settings/MachineManager.py
index 2185bbce9d..755d05d71e 100755
--- a/cura/Settings/MachineManager.py
+++ b/cura/Settings/MachineManager.py
@@ -385,7 +385,6 @@ class MachineManager(QObject):
         self._application.setGlobalContainerStack(global_stack)
         ExtruderManager.getInstance()._globalContainerStackChanged()
         self._initMachineState(global_stack)
-        self._onGlobalContainerChanged()
 
         self.__emitChangedSignals()
 
diff --git a/cura/Settings/SettingInheritanceManager.py b/cura/Settings/SettingInheritanceManager.py
index 12b541c3d8..3815d85e81 100644
--- a/cura/Settings/SettingInheritanceManager.py
+++ b/cura/Settings/SettingInheritanceManager.py
@@ -249,7 +249,6 @@ class SettingInheritanceManager(QObject):
         if self._global_container_stack:
             self._global_container_stack.containersChanged.connect(self._onContainersChanged)
             self._global_container_stack.propertyChanged.connect(self._onPropertyChanged)
-        self._onActiveExtruderChanged()
 
     def _onContainersChanged(self, container):
         self._update_timer.start()